development of a new live attenuated mumps virus vaccine in human deploid cells

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Development of a new live attenuated mumps virus vaccine in human diploid cells.

A new live attenuated mumps vaccine was developed in human diploid cells. The S-12 virus was isolated from a 10-year-old girl showing typical symptoms of mumps infection, the diagnosis was confirmed by a pediatrician. The virus was isolated in green monkey kidney cells, without passage in chick embryo cavity or chick embryo fibroblasts. Attenuation of the wild virus was performed by serial pass...

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Matched case-control study of effectiveness of live, attenuated S79 mumps virus vaccine against clinical mumps.

Mumps virus infection is a potentially serious viral infection of childhood and early adulthood. In China, live, attenuated S(79) mumps virus vaccine has been licensed for pediatric use since 1990. There has been no assessment of its efficacy. Thus, the objective of this study was to determine the effectiveness of live, attenuated S(79) mumps virus vaccine against clinical mumps. Cases were sel...

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Journal title:
archives of razi institute

جلد ۴۲، شماره ۱، صفحات ۱-۱۷

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